Olfactomedin-1 Has a V-shaped Disulfide-linked Tetrameric Structure

Olfactomedin-1 Has a V-shaped Disulfide-linked Tetrameric Structure*

Olfactomedin-1 (Olfm1; also known as noelin and pancortin) is a member of the olfactomedin domain-containing superfamily and a highly expressed neuronal glycoprotein important for nervous system development. It binds a number of secreted proteins and cell surface-bound receptors to induce cell signaling processes. Using a combined approach of x-ray crystallography, solution scattering, analytic...

Spatially Varied Flow Profiles in a V-Shaped Side-Channel

A Comprehensive Model for Stiffness Coefficients in V-Shaped Cantilevers

   During past decade the AFM based nanomanipulation has been focus of attention as the promising nano fabrication approach. The main challenge in this process is the real-time monitoring. Consequently, the dynamic models have been proposed as a solution to the existing challenge. In the modeling approach the magnitudes of the forces are proportional to the stiffness coefficients o...

Resistance to Flow in a V-Shaped Bottom Channel

Water flow in open channels is always subject to the resistance to flow and energy dissipation. For design purposes, one of the needed variables is the hydraulic resistance coefficient. For this mean, the influence of cross-sectional shape together with secondary flow cells and lateral distribution of true boundary shear stress have not yet been fully explored. This paper surveys the number of ...

Complement C1q Has a Novel Tetrameric Structure in Nile Tilapia (oreochromis Niloticus)

Complement C1q is the first subcomponent of the classical complement pathway, and a major molecule connecting link between innate and adaptive immunity. Mammalian C1q is a hexamer of a molecular weight about 410 kDa; however, little is known about its structural characteristics in teleost. In this study, a rapid method for isolation of the C1q (OnC1q) was developed to investigate its biochemica...